Specific Autoantibodies and Clinical Phenotypes Correlate with the Aberrant Expression of Immune-Related MicroRNAs in Dermatomyositis

Figure 2

Correlations between miR-23b-3p, miR-146a-5p, and miR-146b-5p and clinical laboratory parameters of DM. (a) The results showed that miR-23b-3p expressions were negatively correlated with CK (, ). (b) Serum miR-146a-5p levels were significantly correlated with CRP (, ). (c, d) Significant correlations were observed between miR-146b-5p levels and CRP (, ) and ESR (, ). Data were analyzed by Spearman’s rank correlation coefficient. All values were two-sided, and value < 0.05 was statistically considered significant. DM: dermatomyositis; CRP: C-reactive protein; ESR: erythrocyte sedimentation rate; CK: creatine kinase; LDH: lactate dehydrogenase.

(a)

(b)

(c)

(d)