Specific Autoantibodies and Clinical Phenotypes Correlate with the Aberrant Expression of Immune-Related MicroRNAs in Dermatomyositis

Table 3

Serum/plasma expression of miRNAs correlated with clinical phenotypes in DM.

miRNAs	Regulation	Clinical phenotypes	Ref
miR-4442	Up	Skeletal disease activities	[23]
miR-146a	Down	Inflammation	[8]
Let-7b	Up		[11]
miR-3907	Up	Disease activity
miR-4299	Down
miR-7	Down	Gottron’s eruption	[26]
miR-223	Down	Gottron’s papules	[24]
miR-23b-3p	Down	CK	Our study
miR-146a-5p	Down	CRP
miR-146b-5p	Up	ESR, CRP, and DM complicated with cancer
miR-150-5p	Down	Anti-MDA5 and anti-NXP2 antibody

DM: dermatomyositis; CK: creatine kinase; CRP: C-reactive protein; ESR: erythrocyte sedimentation rate; anti-MDA5: anti-melanoma differentiation-associated gene 5; anti-NXP2: anti-nuclear matrix protein-2