Increased TLR4 Expression Aggravates Sepsis by Promoting IFN-γ Expression in CD38^−/− Mice

Figure 1

The LPS infection which induced changes in appearance and weight were more serious in CD38^−/− mice. (a–d) 2 hours post-LPS injection, mouse showed signs of illness in appearance. (e) The percentage of sepsis mouse weight loss 2 hours after LPS infection, WT and CD38^−/− mice, each group contains 5 male mice. (f) The serum creatinine (Scr) level in the WT and CD38^−/− mice 2 hours after PBS or LPS injection. (g–j) CD38^−/− mouse represented more evident encrusted eye. Data are presented as deviation (SD). Statistical significance was determined by the paired -test. , .

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