Efficiency of Multiparticulate Delivery Systems Loaded with Flufenamic Acid Designed for Burn Wound Healing Applications

Table 1

Correlation coefficients for FA release from collagen spongious supports determined by application of Higuchi, Zero-order, and Power law models; kinetic parameters for Power law model; drug-released percentage.

Spongious matrices	Higuchi model	Zero-order model	Power law model	Release exponent	Kinetic constant (1/min^n)	Drug-released percentage (%)
M1	0.9722	0.8741	0.9864	0.37	0.089	86.81
M2	0.9744	0.8566	0.9828	0.41	0.034	85.30
M3	0.9697	0.8430	0.9815	0.40	0.033	76.20
M4	0.9621	0.8264	0.9784	0.39	0.048	95.01
M5	0.9525	0.8041	0.9772	0.36	0.059	91.39

Released drug percentage after 10 hours—FA incorporated in free form; released drug percentage after 48 hours—FA incorporated in multiparticulate systems.