Research Article

The IL-1B Gene Polymorphisms rs16944 and rs1143627 Contribute to an Increased Risk of Coronary Artery Lesions in Southern Chinese Children with Kawasaki Disease

Table 5

Stratification analysis for the association between rs1143627 A>G polymorphism and susceptibility to CALs in Kawasaki disease.

VariablesGG/AGAACrude OR (95% CI)Adjusted ORa (95% CI)a
CALs/NCALs

rs1143627
Age, month
 ≤1274/9850/292.28 (1.32-3.95)0.00322.33 (1.34-4.04)0.0027
 12-60126/19134/630.82 (0.51-1.31)0.3200.83 (0.51-1.33)0.435
 >6021/177/90.63 (0.19-2.04)0.4410.62 (0.19-2.02)0.425
Gender
 Females66/10827/301.47 (0.81-2.69)0.2091.47 (0.80-2.69)0.211
 Males155/19864/711.15 (0.77-1.71)0.1401.16 (0.78-1.73)0.460

aAdjusted for age and gender.