Low-Dose Sirolimus Immunoregulation Therapy in Patients with Active Rheumatoid Arthritis: A 24-Week Follow-Up of the Randomized, Open-Label, Parallel-Controlled Trial

Figure 6

Safety outcomes of liver and renal function. Mean concentration of serum alanine transaminase (a), aspartate aminotransferase (b), blood urea nitrogen (c), and serum creatinine (d) are shown. Overall changes in safety endpoints during treatment were assessed to indicate for each safety outcome. An unpaired -test was used to compare the blood routine measures between the sirolimus and conventional groups. Error bars show SD.

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