Journal of Immunology Research

Review Article

Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells

Table 1

Employment of valproic acid in clinical trials.
Group of diseasesSpecific condition in which VPA has been employedClinicalTrials.gov identifier:
Neurological disordersEpilepsyNCT00385411
Alzheimer’s diseaseNCT01729598
Neuropathic painNCT00221637
Amyotrophic lateral sclerosisNCT00136110
DeliriumNCT02343575
AutismNCT00211796
Psychotic disorderNCT01094249
Bipolar disorderNCT00431522
DepressionNCT00186186
MigraineNCT00195741
DementiaNCT00315900
SchizophreniaNCT00194025
Spinal muscular atrophyNCT00661453
NeuralgiaNCT00221637
Posttraumatic stressNCT00203385
Attention deficit hyperactivity disorderNCT00228046
DependenciesAlcohol abuseNCT01342549
Cocaine dependenceNCT00240110
Marijuana abuseNCT00218114
Opiate dependenceNCT00367874
CancerGliomaNCT00302159
AstrocytomaNCT03243461
MelanomaNCT00358319
Colorectal cancerNCT01898104
Malignant mesotheliomaNCT00634205
LymphomaNCT00854581
Chronic lymphocytic leukemiaNCT02144623
Acute myeloid leukemiaNCT00414310
Thyroid neoplasiaNCT01182285
Brain metastasisNCT00513162
Breast cancerNCT01010854
Nasopharyngeal cancerNCT00181220
Prostate cancerNCT00670046
Bladder cancerNCT01738815
Kaposi’s sarcomaNCT00075777
Small cell lung carcinomaNCT00759824
OthersBronchial asthmaNCT00153270
Autoimmune lymphoproliferative syndromeNCT00605657
Hypersplenism and lymphadenopathyNCT00605657
Retinitis pigmentosaNCT01233609
Focal glomerulosclerosisNCT02896270
Insulin resistanceNCT00552500
Androgenic alopeciaNCT01548066
HematuriaNCT01738815
HIV viral replication controlNCT00289952