miR-223-3p Inhibits Antigen Endocytosis and Presentation and Promotes the Tolerogenic Potential of Dendritic Cells through Targeting Mannose Receptor Signaling and Rhob

Figure 4

miR-223-3p regulated TGF-β1 production in OVA-induced DCs. Immature mouse DCs transfected with the miR-223-3p inhibitor, inhibitor control, miR-223-3p mimic, or mimic control at a final concentration of 50 nM. After 24 h, DCs were stimulated with 100 μg/ml OVA for 24 h. TGF-β1 (a), IL-6 (b), IL-10 (c), and IL-12 (d) levels in the supernatants were measured by ELISA. Data were shown as of three independent experiments. Post hoc Tukey’s HSD test, , .

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