Research Article
Probiotics Can Boost the Antitumor Immunity of CD8+T Cells in BALB/c Mice and Patients with Colorectal Carcinoma
Table 1
The correlation between clinical data and PFS of patients with colorectal carcinoma was analyzed by log-rank test.
| Clinical parameters | Cases | Median PFS (days) | | |
| Gender | | | | | Male | 63 | 1372 | 0.766 | 0.382 | Female | 59 | 1453 | Age | | | | | <59 | 58 | 1334 | 2.023 | 0.155 | ≥60 | 64 | 1480 | CD4+T cells | | | | | Low | 38 | 1408 | 0.097 | 0.756 | High | 84 | 1412 | CD8+T cells | | | | | Low | 35 | 1514 | 9.684 | 0.002 | High | 87 | 1158 | Group | | | | | Group A | 62 | 1531 | 4.622 | 0.032 | Group B | 60 | 1294 | TNM stage | | | | | I-II | 55 | 1566 | 5.878 | 0.015 | III-IV | 67 | 1285 | Pathology grade | | | | | I-II | 80 | 1531 | 7.398 | 0.004 | III-IV | 42 | 1183 | Lymphatic metastasis | | | | | Positive | 48 | 1186 | 8.847 | 0.003 | Negative | 74 | 1558 |
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Note: group A was treated with probiotics before surgery, group B was not treated with probiotics.
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