Thymic Stromal Lymphopoietin Is Implicated in the Pathogenesis of Bullous Pemphigoid by Dendritic Cells

Figure 1

TSLP levels in sera and blister fluids of patients with BP were higher than those in controls. (a) The levels of TSLP in BP sera () were higher than those in HCs (, ). (b) The levels of TSLP in blister fluids of patients with BP () were higher compared to those of other blister dermatoses (, ). (c) The levels of TSLP in sera correlate with those in blister fluids (, , ). (d) The levels of TSLP in blister fluids were slightly higher than those in sera, but no significant differences were detected (). TSLP levels in sera and blister fluids were investigated by enzyme-linked immunosorbent assay. values were determined by the Wilcoxon rank test in (a, b) or the Wilcoxon signed rank test in (d). Correlation was determined by the Spearman rank correlation test in (c). A value of less than 0.05 was considered statistically significant. Column scatter graphs show the median (lower quartile, upper quartile), and the measured values from individual patients were plotted by dots. TSLP: thymic stromal lymphopoietin; BP: bullous pemphigoid; HCs: healthy controls.

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