Evaluation of Four Rapid Tests for Detection of Hepatitis B Surface Antigen in Ivory Coast

Table 1

Performances of Determine™, SD Bioline WB®, Standard Q® and Vikia® for HBsAg detection compared with EIA tests.

	HBsAgserologyEIA		Sensitivity, % (95% CI)	Specificity, % (95% CI)	PPV, % (95% CI)	NPV, % (95% CI)	Accuracy, % (95% CI)	Kappa (95% CI)
	Positive	Négative
Determine™
Positive	551	0	100	100	100	100	100	1
Negative	0	553	(99.17-100)	(99.17-100)	(99.17-100)	(99.17-100)	(99.17-100)
SD Bioline WB®
Positive	548	1	99.46	99.82	99.82	99.46	99.64	0.99
Negative	3	552	(98.33-99.89)	(98.88-100)	(98.87-100)	(98.34-99.89)	(99.04-99.89)	(0.98-1)
Standard Q®
Positive	535	1	97.1	99.82	99.81	97.18	98.46	0.97
Negative	16	552	95.3-98.24	98.88-100	98.84-100	95.44-98.29	97.53-99.06	0.95-0.98
Vikia®
Positive	551	0	100	100	100	100	100	1
Negative	0	553	99.17-100	99.17-100	99.17-100	99.17-100	99.17-100

Abbreviations: PPV, positive predictive value, NPV, negative predictive value, CI, confidence interval.