Research Article

Evaluation of Four Rapid Tests for Detection of Hepatitis B Surface Antigen in Ivory Coast

Table 2

Comparison of Diagnostic accuracy between the plasma/serum and whole of Determine™, SD Bioline WB®, Standard Q® and Vikia® for HBsAg detection.

Sensitivity, % (95% CI)Specificity, % (95% CI)PPV, % (95% CI)NPV,% (95% CI)Accuracy, % (95% CI)P

Determine™
plasma/serum100 (99.17-100)100 (99.17-100)100 (99.17-100)100 (99.17-100)100 (99.17-100)0,91
Wholeblood100 (99.17-100)100 (99.17-100)100 (99.17-100)100 (99.17-100)100 (99.17-100)
SD Bioline WB®
plasma/serum98.84 (95.61-99.95)99.82 (98.88-100)99.82 (98.87-100)98.93 (95.93-99.96)99.64 (99.04-99.89)0,38
Wholeblood100 (99.17-100)100 (99.17-100)100 (99.17-100)100 (99.17-100)100 (99.17-100)
Standard Q®
plasma/serum96.53 (92.47-98.57)99.82 (98.88-100)99.81 (98.84-100)97.18 (95.44-98.29)98.46 (97.53-99.06)0,42
Wholeblood98.05 (94.91-99.42)100 (99.17-100)100 (99.17-100)98.04 (94.89-99.41)99.01 (97.33-99.71)
Vikia®
plasma/serum100 (99.17-100)100 (99.17-100)100 (99.17-100)100 (99.17-100)100 (99.17-100)0,91
Wholeblood100 (99.17-100)100 (99.17-100)100 (99.17-100)100 (99.17-100)100 (99.17-100)

Abbreviations: PPV, positive predictive value, NPV, negative predictive value, CI, confidence interval. Calculated by Fisher’s test.