Genetic Mutations of Tim-3 Ligand and Exhausted Tim-3⁺ CD8⁺ T Cells and Survival in Diffuse Large B Cell Lymphoma

Figure 1

Genetic mutations in galectin-9: (a) an overview of the mutations in galectin-9 in the samples from patients with haematopoietic and lymphoid malignancies, according to the COSMIC database. (b) The substitution mutations of galectin-9 in the haematopoietic and lymphoid cancer samples, according to the COSMIC database. (c) Schematic representation of galectin-9, indicating the location of the mutations identified by targeted deep sequencing in patients with diffuse large B cell lymphoma (DLBCL).

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