Persistent Activation of Innate Immunity in Patients with Primary Antibody Deficiencies

Figure 1

(a) PMN absolute numbers (per μL) of whole peripheral blood of the patients and controls of the study. (b) Representative dot plots of CD64 expression on PMN. (c) CD64 intensity of expression on polymorphonuclear cells (PMN) of the patients and controls of the study. (d) CD16 intensity of expression on whole-blood PMN of the patients and controls of the study at basal state. (e) After incubation of whole blood without and with LPS. The lines represent the median values. Statistical analyses were performed by the Mann–Whitney test. The Wilcoxon-matched paired analysis was performed to compare same subjects under culture conditions; ; ; ns, not significant.