Serum Neuropeptide Y Levels Are Associated with TNF-α Levels and Disease Activity in Rheumatoid Arthritis

Table 3

Results of the multivariate analysis evaluating factors associated with active disease in rheumatoid arthritis patients.

Risk factors of disease activity	Forward method (stepwise)
	OR	95% CI
Serum NPY levels (pg/mL)	1.04	(1.006 to 1.09)	0.03
HAQ-DI score	31.17	(5.90-164.67)	<0.001

Logistic regression models using forward stepwise method. This model was adjusted by age, BMI, body fat mass, and biologic-DMARD use (anti-TNF-α agents). Dependent variable disease activity (active disease defined by and remission DAS28 score of <2.6). OR: odds ratio; 95% CI: 95% statistical significance. .