Quercetin Suppresses AOM/DSS-Induced Colon Carcinogenesis through Its Anti-Inflammation Effects in Mice

Table 1

Metabolite profiling in the serum from the control, AOM/DSS, and quercetin+AOM/DSS groups.

	Control vs. AOM/DSS			Control vs. quercetin+AOM/DSS			AOM/DSS vs. quercetin+AOM/DSS
	VIP	-test	Trend	VIP	-test	Trend	VIP	-test	Trend
2-Hydroxybutyrate	1.4378	0.0011	↑	1.6286	0.0012	↑	2.2176	00028	↓
2-Aminobutyrate	1.2419	0.0025	↑	1.3547	0.0018	↑	1.8765	0.0078	↓
2-Oxobutyrate	1.3043	0.0176	↑	1.2365	0.0043	↑	1.7458	0.0160	↓
Endocannabinoid	1.6786	0.0148	↑	1.4298	0.0035	↑	1.6385	0.0087	↓
Sphinganine	—	—	—	—	—	—	1.6643	0.0492	↓
Gentian violet	1.3345	0.0049	↓	—	—	—	1.4250	0.0087	↑
Indole-3-methyl acetate	1.4261	0.0250	↓	—	—	—	—	—	—
N-Acetyl-5-hydroxytryptamine	1.3276	0.0251	↓	—	—	—	1.3462	0.0132	↑
Indoxyl sulfate	1.3534	0.0142	↓	—	—	—	1.6241	0.0176	↑
Indoxyl	1.7664	0.0352	↓	1.4096	0.0230	↓	1.1295	0.0089	↑

Biomarkers were selected according to the -test (), fold change (<0.6–>1.5), and VIP (>1) results.