Myeloid Cells in Circulation and Tumor Microenvironment of Colorectal Cancer Patients with Early and Advanced Disease Stages

Figure 1

Levels of myeloid cells in whole blood of CRC patients. Peripheral whole blood samples obtained from patients with colorectal cancer (CRC; ) were stained for different myeloid cell markers. Representative flow cytometric plots show the gating strategy identifying granulocytic myeloid cells (GMCs; CD33⁺HLA-DR^-CD15⁺), monocytic myeloid cells (MMCs; CD33⁺HLA-DR^-CD14⁺), immature myeloid cells (IMCs; CD33⁺HLA-DR^-CD15^-CD14^-), and antigen-presenting cells (APCs; CD33⁺HLA-DR⁺CD14⁺) (a). Cumulative scatter plot shows the calculated percentages of the different myeloid cell subsets in whole blood of CRC patients (b). The values are represented as follows: . Data depict the .

(a)

(b)