An Immune Atlas of Nephrolithiasis: Single-Cell Mass Cytometry on SIRT3 Knockout and Calcium Oxalate-Induced Renal Injury

Figure 1

Characterization of immune cells in nephrolithiasis using mass cytometry. (a) Schematic showing how clusters are related to parent populations. (b) t-SNE maps displaying 9935 cells from the nephrolithiasis models analyzed with 42-antibody panel and colored by the main cell populations. (c) Heatmap showing normalized expression of the markers from 42-antibody panel for PhenoGraph clusters. Clusters are grouped by expression profiles, and cell types are indicated by color. The cluster IDs and relative frequencies are displayed as a bar graph on the left.

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