Lentinan Attenuates Damage of the Small Intestinal Mucosa, Liver, and Lung in Mice with Gut-Origin Sepsis

Figure 6

Lentinan downregulates the NF-κB signaling pathway and thus inhibits apoptosis of intestinal epithelial cells. (a) Western blot was used to detect the protein expression of TLR4, NF-κB, Bcl-2, occludin, and Bax in the small intestine tissue of each group. (b) Quantifications of western blots. (c) RT-qPCR was adopted for detecting the mRNA expression of TLR4, NF-κB, Bcl-2, occludin, and Bax in the small intestine of each group. The experimental results were expressed in the form of the (SD). vs. sham group. ^# and ^## vs. CLP group.

(a)

(b)

(c)