Research Article

Immunomodulatory Effects of Canine Adipose Tissue Mesenchymal Stem Cell-Derived Extracellular Vesicles on Stimulated CD4+ T Cells Isolated from Peripheral Blood Mononuclear Cells

Table 1

Comparison of CD4+, CD8+, CD4+CD8+, and CD4-CD8- T cell populations after coculture of PBMCs with cADSC-EVs.

ControlNaive EVsPrimed EVs
1 μg/ml5 μg/ml10 μg/ml1 μg/ml5 μg/ml10 μg/ml

CD4+
CD8+
CD4+CD8+
CD4-CD8-

Data are shown as the . The ratio of T cell subset was not significantly different between naive and primed EVs at the same concentrations. vs. control (PBMCs that were not cocultured with cADSC-EVs). vs. control.