Aberrant Expression of a Proliferation-Inducing Ligand Underlies Autoimmune Mechanisms in Immune Thrombocytopenia

Figure 3

Plasma APRIL levels in ITP patients. (a) Plasma APRIL levels were higher in chronic and newly diagnosed ITP patients than in normal controls ( per group), with no significant difference between the two patient groups. (b) APRIL concentration was negatively correlated with platelet count in ITP patients (). (c) Correlation between platelet surface APRIL and serum APRIL levels in ITP patients. (d–f) Differences in Plasma APRIL levels before and after treatment in the chronic ITP patient group () (d) in the complete remission group () (e) and the nonresponse group () (f).

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