circ_0001588 Induces the Malignant Progression of Hepatocellular Carcinoma by Modulating miR-874/CDK4 Signaling

Figure 6

circ_0001588 enhanced the proliferation, migration, and invasion of HCC via targeting the miR-874/CDK4 pathway. (a, b) mRNA expression of CDK4 in HCC cells transfected with circ_0001588-OE and miR-874 mimics. (c, d) The growth curves were tested by CCK-8 assays. (e, f) Cell apoptosis was tested using flow cytometry. (g, h) Cell migration and invasion assays were conducted in HCC cells. .

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