Immunization with CENP-C Causes Aberrant Chromosome Segregation during Oocyte Meiosis in Mice

Figure 4

Effects of the CENP-C antibody on oocyte maturation. Oocytes during germinal vesicle breakdown were detected after 3 hours of culture from GV oocytes. Oocytes during first polar body (Pb1) extrusion were observed after 14 hours of in vitro maturation of GV oocytes. (a) Quantitative analysis of GVBD in the control group and experimental group ( vs. control, ). (b) Quantitative analysis of Pb1 extrusion in the control group and experimental group ( vs. control, ). Data were expressed as from 3 independent experiments. .

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(b)