Th17/1-Biased Inflammatory Environment Involved in the Response of Epithelial Cells to Antigen Stimuli in Nasal Polyps

Figure 6

Effect of a Th17/1 environment on the proinflammatory response of NP69 cell to stimuli. NP69 cells were cultured in the presence or absence of human IFN-γ and IL-17A for 48 hours, then stimulated with either poly I:C or LPS for 4 h in serum-free media. (a) Summary data showed IL-6 and IL-8 expression levels by NP69 cells (). (b) Summary data showed mRNA expression of IL-6, IL-8, TNF-α, and IL-1β in NP69 cells (). Data were shown as the . Statistical significance was determined with the Mann–Whitney test. ; ; .

(a)

(b)