Development and Validation of a Robust Immune-Related Prognostic Signature for Gastric Cancer

Table 1

The 45 intersection prognosis-related genes identified by univariate Cox regression analysis in the training cohort.

Gene list	Category	HR	HR.95L	HR.95H
AGTR1	Cytokine_receptors	1.334317	1.217829	1.461947
AKT3	BCRSignalingPathway	1.761968	1.444244	2.149589
ANGPTL2	Cytokine_receptors	1.344887	1.192773	1.5164
BMPR2	Cytokine_receptors	2.362857	1.701484	3.28131
BPHL	Antimicrobials	0.637487	0.504375	0.80573
CLEC11A	Cytokines	1.516036	1.301901	1.765391
CMTM3	Cytokines	1.939969	1.499121	2.510458
CRIM1	Cytokine_receptors	1.923839	1.533551	2.413454
CTGF	Cytokines	1.603191	1.381789	1.860068
CYR61	Cytokines	1.384955	1.224587	1.566325
DAK	Antimicrobials	0.586742	0.442452	0.778088
DES	Antimicrobials	1.205936	1.13654	1.279568
EDNRA	Chemokine_receptors	1.499985	1.315628	1.710175
ELN	Antimicrobials	1.490388	1.305397	1.701595
ENG	Cytokine_receptors	1.391229	1.18348	1.635447
ESM1	Cytokines	1.462723	1.244433	1.719303
GNAI1	Antimicrobials	1.427925	1.196914	1.703522
GREM1	Cytokines	1.317087	1.181972	1.467647
GRP	Cytokines	1.227876	1.140799	1.321601
HDGFRP3	Cytokines	1.603254	1.380716	1.86166
IL1R1	Cytokine_receptors	1.613095	1.373481	1.894511
INHBB	TGFb_family_member	1.544374	1.362625	1.750365
LTBP3	Cytokines	1.722496	1.358221	2.184469
NOV	Cytokines	1.563551	1.372153	1.781646
NOX4	Antimicrobials	1.639326	1.41234	1.902793
NPR3	Cytokine_receptors	1.849908	1.547669	2.21117
NR2F1	Cytokine_receptors	1.378966	1.224325	1.55314
NRP1	Cytokine_receptors	1.707208	1.420286	2.052093
NRP2	Cytokine_receptors	1.691583	1.393531	2.053385
OSMR	Cytokine_receptors	1.74949	1.417618	2.159056
OXTR	Cytokine_receptors	1.405633	1.201078	1.645026
PDGFC	Cytokines	1.619596	1.361091	1.927198
PDGFRB	Cytokines	1.508678	1.304742	1.744491
PTGER3	Cytokine_receptors	1.630084	1.371071	1.938027
RBP1	Antimicrobials	1.486226	1.289005	1.713621
SDC2	Cytokine_receptors	1.822409	1.522803	2.180962
SEMA4C	Chemokines	2.225396	1.693848	2.92375
SHC4	NaturalKiller_cell_cytotoxicity	1.926967	1.615581	2.298371
SLIT2	Chemokines	1.469846	1.32759	1.627345
STC2	Cytokines	1.506128	1.26909	1.78744
TGFB2	Cytokines	2.056681	1.636983	2.583983
TGFB3	Cytokines	1.5918	1.342242	1.887756
THBS1	Antigen_processing_and_presentation	1.487585	1.310701	1.688341
TNC	Chemokines	1.286883	1.174997	1.409424
TPM2	Antimicrobials	1.441131	1.297227	1.600998