Correlation Analysis between Gut Microbiota and Metabolites in Children with Systemic Lupus Erythematosus

Figure 2

PCoA analysis and PCA analysis were conducted by R version 3.5.1. The red dots represent health controls, and the blue dots represent systemic lupus erythematosus patient samples. PCoA analysis sorts a series of eigenvalues and eigenvectors. It selects the most important eigenvalues ranked in the first few and shows them in the coordinate system. The result can be regarded as a rotation of the distance matrix. The red dots and the blue dots distribute in different clusters on the coordinate axis, revealing a clear separation between the SLE and HC groups. PCA analysis uses variance decomposition to reflect the differences of multiple groups of data on the two-dimensional coordinate graph. The PCA analysis of our study did not show clear separation.