Crosstalk between RNA-Binding Proteins and Immune Microenvironment Revealed Two RBP Regulatory Patterns with Distinct Immunophenotypes in Periodontitis

Figure 3

Immunocyte infiltration status in periodontitis and their correlation with RBPs. (a) Correlation analysis between relative enrichment score of immunocytes and RBP expression levels. (b) Dot plot and box plot reveal the relationship between the most positively correlated immunocyte-RBP pair, activated_B_cell, and ISG20, with a higher enrichment score of activated_B_cell and higher expression of ISG20 in periodontitis samples. (c) Dot plot and box plot reveal the relationship between the most negatively correlated immunocyte-RBP pair, activated_B_cell, and ESRP1. A higher enrichment score of activated_B_cell and lower expression of ESRP1 were observed in periodontitis samples.