Crosstalk between RNA-Binding Proteins and Immune Microenvironment Revealed Two RBP Regulatory Patterns with Distinct Immunophenotypes in Periodontitis

Figure 5

HLA expression status in periodontitis and their correlation with RBPs. (a) Correlation analysis between HLA and RBP expression levels. (b) Dot plot and box plot reveal the relationship between the most positively correlated HLA-RBP pair, HLA-DOB, and ISG20. Higher expressions of HLA-DOB and ISG20 were observed in periodontitis samples. (c) Dot plot and box plot reveal the relationship between the most negatively correlated HLA-RBP pair, HLA-DOB, and ESRP1. Higher expression of HLA-DOB and lower expression of ESRP1 were observed in periodontitis samples.