Transcriptional Profiling Reveals Kidney Neutrophil Heterogeneity in Both Healthy People and ccRCC Patients

Figure 1

scRNA-seq analysis of CD45+ cells in healthy kidney. (a) UMAP plot shows clustering results from CD45+ cells from healthy kidney. They are NK cells, neutrophils, Th cell, nephron epithelial cell, and B cells (dot size at 0.5). (b) Pie plot indicates the frequency of each cell type. (c) Feature plots show the expression of known markers for each cluster. (d) UMAP plot shows 2 subclusters of neutrophils in healthy kidney (dot size at 4). (e) Violin plots show the differential expression levels of selected 2 genes from each neutrophil subcluster.

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