Research Article
IFI44L as a Forward Regulator Enhancing Host Antituberculosis Responses
Figure 3
Relative levels of IFI44L and survival of M. tuberculosis H37Rv in the presence of shRNA-IFI44L. (a, b) THP-1 cells transfected with IFI44L-specific shRNA (shRNA-IFI44L) and its scramble shRNA (Scr-shRNA) followed by M. tuberculosis H37Rv infection. (c) Survival of M. tuberculosis H37Rv augmented by CFUs in the presence of shRNA-IFI44L. (d, e) M. tuberculosis H37Rv-infected THP-1 cells with shRNA-IFI44L exhibiting significantly decreased cell apoptosis, as shown in flow cytometry. Values are presented as levels relative to β-actin. ; .
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