METTL3 Intensifies the Progress of Oral Squamous Cell Carcinoma via Modulating the m6A Amount of PRMT5 and PD-L1

<div>METTL3 intensified OSCC cell proliferation and metastasis and suppressed CD8+ T cell activation. (a) qRT-PCR results displayed that METTL3 amount was higher after transfection with METTL3 overexpression vectors. (b, c) METTL3 overexpression suppressed CD8+ T cell activation. (d, e) CCK8 and EdU assays displayed that METTL3 overexpression accelerated OSCC cell proliferation. (f) Wound healing assay displayed that METTL3 overexpression accelerated the competence of OSCC cell migration. 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Journal of Immunology Research

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Figure 3

Figure 3: METTL3 Intensifies the Progress of Oral Squamous Cell Carcinoma via Modulating the m6A Amount of PRMT5 and PD-L1 