Research Article
METTL3 Intensifies the Progress of Oral Squamous Cell Carcinoma via Modulating the m6A Amount of PRMT5 and PD-L1
Figure 7
Silencing PRMT5 and PD-L1 attenuated the occurrence and development of OSCC. (a) The amount of PRMT5 in SCC-9 and CAL-27 cells after being transfected with sh-PRMT5. (b) sh-PD-L1 intensified the immune activity of T cells. (c, d) CCK8 and EdU assays displayed that sh-PRMT5 attenuated OSCC cell proliferation. (e) Wound healing assay displayed that sh-PRMT5 suppressed the competence of OSCC cell migration. (f) Transwell assays displayed that sh-METTL3 attenuated the competence of OSCC cell invasion. , , and .
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