METTL3 Intensifies the Progress of Oral Squamous Cell Carcinoma via Modulating the m6A Amount of PRMT5 and PD-L1

Figure 8

METTL3 promotes OSCC progression through PRMT5 and PD-L1. (a) METTL3 OE could not reverse or weaken the effect of sh-PD-L1 on the immune activity of CD8+ T cells. (b) EdU assay displayed that overexpression of METTL3 could not eliminate or weaken the inhibition of sh-PRMT5 on cell proliferation. (c) Overexpression of METTL3 could not eliminate or weaken the inhibition of sh-PRMT5 on cell migration. (d) Overexpression of METTL3 could not eliminate or weaken the inhibition of sh-PRMT5 on cell invasion. ns: no statistical significance.

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