Chinese Traditional Medicine NiuBeiXiaoHe (NBXH) Extracts Have the Function of Antituberculosis and Immune Recovery in BALB/c Mice

Figure 5

GO analysis of DE genes between before and after M. tuberculosis infection and INH or NBXH-H treatment. The top 10 GO terms involved in upregulated DE genes between TB-infected mice and normal mice ((a) Water vs. NC), between INH-treated mice and TB-infected mice ((b) INH vs. Water), or between NBXH-H-treated mice and TB-infected mice ((c) NBXH-H vs. Water) were, respectively, identified in BP, CC, and MF. Similarly, the top 10 GO terms involved in downregulated DE genes between the Water vs. NC groups (d), the INH vs. Water groups (e), or the NBXH-H vs. Water groups (f) were identified in BP, CC, and MF, respectively. The enrichment score is shown as -log10 ( value); the value denotes the significance of GO Term enrichment in the DE gene list. The less the value is, the more significant of the GO Term is ( is recommended). BP: biological process; CC: cellular component; MF: molecular function.

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