Research Article

Chinese Traditional Medicine NiuBeiXiaoHe (NBXH) Extracts Have the Function of Antituberculosis and Immune Recovery in BALB/c Mice

Table 3

The significant upregulated genes after NBXH-H treatment.

GenBank accessionGene nameFCAbsoluteGene ontology annotations
Water vs. NCINH vs. WaterNBXH-H vs. WaterCellular componentMolecular functionBiological process

AK0147044833415N18RikNo62 (↑)186 (↑)NoNoNo
NM_146630Olfr1234 (↓)73 (↑)100 (↑)MembraneNoCellular process
NM_001166464Spock19 (↓)28 (↑)92 (↑)Cell partBinding molecular functionCellular process
NM_021455MlxiplNo73 (↑)76 (↑)Cell partBinding molecular functionPositive regulation of biological process
NM_010916Nhlh12 (↓)52 (↑)72 (↑)Cell partBinding molecular functionCellular process
XR_141090No120 (↑)68 (↑)
NM_133893Oas1d2 (↑)81 (↑)67 (↑)IntracellularBinding molecular functionMetabolic process, biological regulation
AK087822Gm7644No37 (↑)63 (↑)NoNoNo
NM_001013362NpcdNo34 (↑)60 (↑)Cell partBinding molecular functionNo
AK0358409030624J02Rik5 (↓)22 (↑)58 (↑)No
NM_016916BlcapNo45 (↑)57 (↑)MembraneNoCellular process
AK089977Gm56083 (↓)40 (↑)49 (↑)NoNoNo
NM_175164Arhgap26No27 (↑)46 (↑)Cell partBinding molecular functionCellular process
NM_029797Mnd1NoNo46 (↑)Cell partBinding molecular functionCellular process
NM_011192Psme3No26 (↑)46 (↑)Cell partBinding molecular functionCellular process
NM_178227Scn3bNo15 (↑)44 (↑)Cell partBinding molecular functionLocalization
NM_207017Tas2r1095 (↓)27 (↑)43 (↑)MembraneNoCellular process
NM_016694Park2No68 (↑)41 (↑)Cell partBinding molecular functionLocalization
NM_009299SvaNo17 (↑)41 (↑)Extracellular spaceNoCellular process
NM_053104Rbfox2No17 (↑)41 (↑)Cell partBinding molecular functionCellular process
NM_001253361Kcnma15 (↓)41 (↑)40 (↑)Cell partBinding molecular functionLocalization
NM_001077499Scn8aNo43 (↑)40 (↑)Cell partBinding molecular functionLocalization
NM_026680Golt1aNo54 (up)40 (↑)Cell partNoLocalization

FCAbsolute: absolute ratio (no log scale) of normalized intensities between two groups. was selected. ↑: upregulated; ↓: downregulated; No: not found in the database.