Serum CD4 Is Associated with the Infiltration of CD4⁺T Cells in the Tumor Microenvironment of Gastric Cancer

Table 1

Patient characteristics.

Variables	Number of patients	Percentage
Sex
Male	166	76.1
Female	52	23.9
Age (years)^a
<70	180	82.6
≥70	38	17.4
Borrmann classification^b
Type I	38	17.4
Type II	45	20.6
Type III	89	40.8
Type IV	46	21.1
Vascular invasion
Absent	132	60.6
Present	86	39.4
Neural invasion
Absent	82	37.6
Present	136	62.4
TNM stage^C
I	39	17.9
II	58	26.6
III	107	49.1
IV	14	6.4
Lymph node ratio (involved/examined lymph nodes)
0	66	30.3
>0 to ≤0.3	85	39.0
>0.3 to ≤0.6	44	20.2
>0.6	23	10.6
WHO classification
Well to moderately differentiated	96	44.0
Poorly differentiated	55	25.2
Signet ring cell	54	24.8
Mucinous	13	6.0
Tumor location
Lower third	143	65.6
Middle third	41	18.8
Upper third	18	8.3
Entire stomach	16	7.3

^aMedian age: 61 years, range 30–83 years. ^bBorrmann type I: polyp type; Borrmann type II: local infiltration type; Borrmann type III: ulcer type; Borrmann type IV: diffusely infiltrative type. ^CBased on the 8th edition of the AJCC Cancer Staging Manual of the American Joint Committee on Cancer.