Schistosoma japonicum Infection in Treg-Specific USP21 Knockout Mice

Figure 4

Liver immunity in USP21^fl/flFOXP3^cre mice infected with S. japonicum. (a) Representative images of USP21 protein expression in the in WT and KO mice in the NC and INF groups determined using Western blotting ( mice/group). (b) Comparison of protein expression in the WT and KO mice in the NC and INF groups ( mice/group). The data are presented as the , and the difference between the infection groups was significant (). (c) Comparison of the USP21 mRNA levels between WT and KO mice in the NC and INF groups ( mice/group). The data are presented as the , for the comparison between the infection groups. (d) Comparison of the levels of the FOXP3, IL-10, and IL-17 mRNAs in the WT and KO mice from the NC and INF groups ( mice/group). The data are presented as the ; for the comparison between the infection groups: IL-10 and IL-17 .

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