IL-13 Augments Histone Demethylase JMJD2B/KDM4B Expression Levels, Activity, and Nuclear Translocation in Airway Fibroblasts in Asthma

Figure 5

JMJD2B expression in asthmatic bronchial biopsy tissues. Representative bronchial biopsy sections from healthy control showing weak and asthmatic showing moderate to strong JMJD2B protein expression. Representative images for H&E staining taken at 10x magnification and IHC for JMJD2B taken at 20x magnification showing developed with 3,3- diaminobenzidine (brown). Nuclei were counterstained with hematoxylin (blue). Arrows refer to bronchial epithelium. Arrowheads refer to fibroblasts.