RNA-seq and In Vitro Experiments Reveal the Protective Effect of Curcumin against 5-Fluorouracil-Induced Intestinal Mucositis via IL-6/STAT3 Signaling Pathway

Figure 4

Effect of curcumin on the IL-6/STAT3 signaling in the 5-FU-stimulated IEC-6 cells. Western blotting assay was performed to detect the protein expression levels of E-cadherin, vimentin, N-cadherin, IL-6, and p-STAT3 in each group cells. Data were expressed as (SEM), ^▲▲ value < 0.01 vs. control group; value < 0.05 vs. 5-FU group; value <0.01 vs. 5-FU group. 5-FU: 5-fluorouracil.