Research Article

Salivary Interleukin-6 and C-Reactive Protein/Mean Platelet Volume Ratio in the Diagnosis of Late-Onset Neonatal Pneumonia

Table 3

Diagnostic performance of the tested markers for detection of late-onset neonatal pneumonia.

ParameterAUC95% CICutoff valueSensitivity (%)Specificity (%)PPV (%)NPV (%)

Salivary IL-6 (pg/ml)0.9070.833–0.981>3482.8691.4390.684.2
Serum IL-6 (pg/ml)0.9210.848–0.993>15.388.5788.5788.688.6
MPV(fl)0.7560.641–0.872>9.785.7168.5773.282.8
CRP/MPV ratio0.9950.990–1.0>0.8897.1485.7187.296.8

IL-6: interleukin-6; MPV: mean platelet volume; CRP: C-reactive protein.