Transcriptome Analysis of Large to Giant Congenital Melanocytic Nevus Reveals Cell Cycle Arrest and Immune Evasion: Identifying Potential Targets for Treatment

<div>PPI network construction and key module detection. (a) PPI network of the DEGs created using Cytoscape. The genes of the key module are in yellow, whereas the other DEGs are in blue. (b) Key module identified using the MCODE plug-in of Cytoscape. The key module possesses the most frequent and closest interactions in the PPI network. (c) Heatmap and cluster analysis of key module genes. Red and blue depict relative gene expression levels from high to low. Heatmap scale: row; cluster method: ward; D2; row distance measure: Euclidean; row distance measure: Euclidean. PPI: protein–protein interaction; DEGs: differentially expressed genes; MCODE: molecular complex detection.</div>

Journal of Immunology Research

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Figure 2: Transcriptome Analysis of Large to Giant Congenital Melanocytic Nevus Reveals Cell Cycle Arrest and Immune Evasion: Identifying Potential Targets for Treatment 

Figure 2 | Transcriptome Analysis of Large to Giant Congenital Melanocytic Nevus Reveals Cell Cycle Arrest and Immune Evasion: Identifying Potential Targets for Treatment 