Impacts of Chemokine (C-X-C Motif) Receptor 2 C1208T Polymorphism on Cancer Susceptibility

Table 1

Study characteristics of CXCR2 C1208T polymorphism in the present analysis.

Author; C1208T	Year	Origin	Type	Race	Source	Genotype	Case						Control
							Age (y)	TT	TC	CC	Total	HWE	Age (y)	TT	TC	CC	Total	HWE
Kamangar	2006	Finland	GC	European	PB	TaqMan	Mean 58.5	36	61	15	112	0.172	59 (50-69)	66	108	34	208	0.359
Brown	2006	Italy	KS	European	PB	TaqMan	72 (29-91)	14	40	79	133	0.016	75 (37-92)	16	69	87	172	0.666
Lee	2007	China	LC	East Asian	PB	PCR	NA	55	47	13	115	0.542	NA	44	51	12	107	0.628
Sarvestani	2007	Iran	BC	West Asian	HB	PCR	49.4 (28-85)	27	85	106	218	0.131	NA	27	114	120	261	0.992
Andrew	2009	USA	BLCA	European	PB	GoldenGate	64 (25-74)	250	255	84	589	0.149	NA	299	414	150	863	0.745
Snoussi	2010	Tunisia	BC	African	HB	PCR		47	167	195	409	0.222		18	128	155	301	0.207
Bondurant	2013	USA	CC	European	PB	GoldenGate	30-79	343	794	417	1554	0.340	NA	411	1009	536	1956	0.112
Bondurant	2013	USA	RC	European	PB	GoldenGate	30-79	201	359	192	752	0.216	NA	199	470	290	959	0.736
Singh	2014	India	BLCA	West Asian	HB	PCR		15	73	112	200	0.520		14	90	96	200	0.247
Ryan	2015	USA	LC	European	PB	iPlexGold		90	215	138	443	0.708		115	238	121	474	0.924
Ryan	2015	Japan	LC	East Asian	PB	TaqMan		170	160	54	384	0.104		178	170	35	383	0.537

BC: breast cancer; BLCA: bladder cancer; BT: biliary tract; CC: colon cancer; GC: gastric cancer; EC: esophageal cancer; KS: Kaposi sarcoma; LC: lung cancer; NA: not available; RC: rectal cancer.