Killer-Cell Immunoglobulin-Like Receptors (KIR) in HIV-Exposed Infants in Cameroon
Table 2
KIR gene frequencies stratified by disease status.
KIR gene
HIV status
aOR (95% CI)
Negative, (%)
Positive (%)
Inhibitory
2DL1
43 (65.2)
7 (50.0)
0.74 (0.22-2.51)
0.632
2DL2
48 (72.7)
11 (78.6)
1.71 (0.38-7.64)
0.478
2DL3
58 (87.9)
13 (92.9)
1.62 (0.13-20.68)
0.705
2DL4
66 (100.0)
14 (100.0)
—
—
2DL5
48 (72.7)
5 (35.7)
0.31 (0.10 - 0.93)
0.028
3DL1
58 (87.9)
11 (78.6)
0.68 (0.20-2.24)
0.521
3DL2
66 (100.0)
14 (100.0)
—
—
3DL3
66 (100.0)
14 (100.0)
—
—
Activating
2DS1
24 (36.4)
0 (0.0)
—
0.023
2DS2
57 (86.4)
12 (85.7)
1.16 (0.27-5.09)
0.843
2DS3
33 (50.0)
6 (42.9)
0.82 (0.23-2.92)
0.762
2DS4
50 (75.8)
11 (78.6)
1.75 (0.40-7.59)
0.451
2DS5
32 (48.5)
2 (14.3)
0.14 (0.02-1.11)
0.029
3DS1
20 (30.3)
3 (21.4)
0.70 (0.15-3.31)
0.647
Pseudogene
2DP1
44 (66.7)
14 (100.0)
0.45 (0.12 - 1.71)
0.230
The HIV-negative group comprises 66 infants (27 born to HIV-negative mothers and 39 to HIV+ parents). HIV-positive infants . aOR: the Mantel-Haenszel odds ratio adjusted for sex, type of delivery, and feeding practice. : adjusted values.
