Killer-Cell Immunoglobulin-Like Receptors (KIR) in HIV-Exposed Infants in Cameroon
Table 3
KIR distribution among HIV-exposed infants.
KIR gene
HIV exposed
aOR (95% CI)
Uninfected, (%)
Infected (%)
Inhibitory
2DL1
20 (51.3)
7 (50.0)
1.18 (0.29-4.75)
0.814
2DL2
27 (69.2)
11 (78.57)
1.89 (0.33-10.68)
0.461
2DL3
34 (87.2)
13 (92.86)
1.78 (0.12-25.44)
0.668
2DL4
39 (100)
14 (100.0)
—
—
2DL5
32 (82.1)
5 (35.7)
0.20 (0.05-0.72)
0.006
3DL1
33 (84.6)
11 (78.6)
0.67 (0.18-2.46)
0.540
3DL2
39 (100.0)
14 (100.0)
—
—
3DL3
39 (100.0)
14 (100.0)
—
—
Activating
2DS1
14 (35.9)
0 (0.0)
—
0.022
2DS2
31 (79.5)
12 (85.7)
1.77 (0.39-8.10)
0.453
2DS3
19 (48.7)
6 (42.9)
0.89 (0.21-3.84)
0.875
2DS4
27 (69.2)
11 (78.6)
2.05 (0.42-9.98)
0.366
2DS5
21 (53.9)
2 (14.3)
0.06 (0.00-1.09)
0.009
3DS1
11 (28.2)
3 (21.4)
1.04 (0.17-6.41)
0.965
Pseudogene
2DP1
25 (64.1)
14 (100.0)
0.60 (0.15-2.49)
0.482
Fifty-three (53) infants were born to HIV-infected mothers, 39 were uninfected by 6 weeks of age, and 14 were HIV infected. aOR: the Mantel-Haenszel odds ratio adjusted for sex, type of delivery, and feeding practice. : adjusted values.
