Intratumoral IL-28B Gene Delivery Elicits Antitumor Effects by Remodeling of the Tumor Microenvironment in H22-Bearing Mice

Figure 3

Intratumoral IL-28B gene transfer did not change the tumor-infiltrating regulatory T cells. The frequencies of CD4⁺, CD8⁺, Foxp3⁺, and CD4⁺Foxp3⁺ cells in TME. (a) Representative dot plots and percentages of cells bounded by each region are shown in panels. (b) Statistical analysis of the percentages of CD4⁺, CD8⁺, Foxp3⁺, and CD4⁺Foxp3⁺ cells in TME were shown (below panels). Data from one experiment, each performed with three mice, are shown. ; ns indicated .

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