Intratumoral IL-28B Gene Delivery Elicits Antitumor Effects by Remodeling of the Tumor Microenvironment in H22-Bearing Mice

Table 1

Intratumoral IL-28B gene transfer reduced tumor growth in a subcutaneous H22 hepatoma model.

Group	Tumor volume (mm^3)	Tumor weight (g)	Tumor inhibition rate (%)
Untreated			—
Cisplatin			17.90
rAd-EGFP			—
rAd-mIL-28B			34.07

The tumor volume was calculated using the formula. The tumor inhibition rate was calculated as follows: . The one-way analysis of variance (ANOVA) was used to determine the statistical significance () between multiple groups. for rAd-mIL-28B vs. rAd-EGFP.