Research Article
29 m6A-RNA Methylation (Epitranscriptomic) Regulators Are Regulated in 41 Diseases including Atherosclerosis and Tumors Potentially via ROS Regulation – 102 Transcriptomic Dataset Analyses
Figure 10
Macrophage polarization regulated the expression of m6A-RNA methylation regulators (m6A-RMRs). Macrophage polarization microarray analysis result showed that expression of WTAP is significantly upregulated in M1 with a fold change of 10.578 and in M2b with a fold change of 2.415 compared with M0 cells; expression of IGF2BP2 is upregulated in M1, M2a, and M2c cells; RBMX is the common downregulated m6A-RMRs in M1, M2a, M2b, and M2c macrophages.