29 m⁶A-RNA Methylation (Epitranscriptomic) Regulators Are Regulated in 41 Diseases including Atherosclerosis and Tumors Potentially via ROS Regulation – 102 Transcriptomic Dataset Analyses

Figure 13

Proinflammatory cytokines can regulate m⁶A-RNA methylation regulators (m⁶A-RMRs). In deficiency of proinflammatory cytokine microarrays, the number of upregulated m⁶A-RMRs is more than that of downregulated m⁶A-RMRs. That is, maybe, proinflammatory cytokines negatively regulate m⁶A methylation. The result is consistent with the result of the m⁶A-RMRs’ expression in acute inflammation.