29 m⁶A-RNA Methylation (Epitranscriptomic) Regulators Are Regulated in 41 Diseases including Atherosclerosis and Tumors Potentially via ROS Regulation – 102 Transcriptomic Dataset Analyses

Table 4

Comparison of our study with other three studies about cardiovascular disease.

m^6A-RMRs	Results in our study (Figure 4(a))	Table 1 in PMID: 34489709	Table 1 in PMID:34221238	Table 1 in PMID: 32910911
	M^6A-RMRs in atherosclerosis	RNA methylation-related enzymes in CVDs	Roles and mechanisms of RNA m^6A effectors in CVDs	The association between m^6A methylation and CVDs
Upregulated genes	PCIF1, YTHDC2, IGF2BP2, IGF2BP3, HNRNPC, PRRC2A, ELAVL1	METTL3, YTHDF2, METTL14, KIAA1429,	N/A	METTL14
Downregulated genes	METTL14, KIAA1429,ZC3H13, FTO, YTHDF3, HNRNPA2B1, FMR1, G3BP1, G3BP2	FTO	ALKBH5, YTHDF2	FTO
Genes without expression changes	METTL3, CBLL1, RBM15B, YTHDF1, YTHDF2, EIF3A, IGF2BP1	N/A	N/A	N/A
Expression of genes not known	METTL16, YTHDC1, RBMX	N/A	N/A	N/A
Uncertain (paradox)	WTAP, RBM15, ALKBH5	YTHDF1	METTL3, FTO, WTAP	METTL3

Abbreviations: CVDs: cardiovascular diseases; N/A: not available.