NLRP3 Inflammasome Simultaneously Involved in Autophagy and Phagocytosis of THP-1 Cells to Clear Aged Erythrocytes

Figure 7

The amounts of IL-1β and caspase-1 detected by ELISA. (a) The concentrations of IL-1β of three different THP-1 cells after receiving the same stimulation in nine groups. (b) The concentrations of caspase-1 of three different THP-1 cells after receiving the same stimulation in nine groups. (c)–(e) The concentrations of IL-1β of wild-type, shNC, and ID3 THP-1 cells after phagocytosis of erythrocytes. (f)–(h) Regulatory effect of BafA1 on IL-1β secretion. (i)–(k) The concentrations of caspase-1 of wild-type, shNC, and ID3 THP-1 cells after phagocytosis of erythrocytes. (l)–(n) Regulatory effect of BafA1 on caspase-1 expression. , , and ns: not significant.

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